Paul Marques’s research career began in 1968 with studies of neuroactive and psychoactive substances, and with studies of CNS temperature regulation and the control of neuroendocrine function. After 5 years of postdoctoral study at the University of Washington in Seattle, his interests shifted into studies of the social consequences of drug and alcohol excess, and in the evaluation of technologies that can detect, monitor, and deter excessive usage that endangers the public’s health and safety.
His intervention populations have included postpartum cocaine involved mothers and alcohol impaired driving offenders. Paul and PIRE colleagues have published studies of alcohol ignition control devices and programs spanning 25+ years. This has included the predictive utility of the interlock BAC test log data, study of state and province-wide interlock outcome studies, evaluation of the adequacy of transdermal alcohol monitoring devices, and the benefits of more widespread use of objective alcohol biomarker measures of consumption, especially blood phosphatidylethanol and hair ethylglucuronide. He has conducted and coordinated multinational laboratory studies of alcohol biomarkers with colleagues in Sweden, Luxembourg, Germany, Canada, and the US in order to evaluate comparative risk monitoring and interventions on alcohol impaired driving offenders.
Since 1989, Paul has been the Principal Investigator on research awards from the NIDA, NIAAA, RWJ, and NHTSA. He has served on NIH grant review committees and the Executive Board of the International Council of Alcohol Drugs and Traffic Safety.
Since 2014, Paul has been an engaged volunteer for trail patrol and charitable work in the Coronado National Forest in Tucson. Marques retired from active research studies in 2014 but still consults on interlock research projects.
Marques, P. R., Tippetts, A. S., & Yegles, M. (2014). Ethylglucuronide in hair is a top predictor of impaired driving recidivism, alcohol dependence, and a key marker of the highest BAC interlock tests. Traffic Injury Prevention, 15(4), 361-369. https://doi.org/10.1080/15389588.2013.824569
Marques, P. R. (2012). Levels and types of alcohol biomarkers in DUI and clinic samples for estimating workplace alcohol problems. Drug Testing and Analysis, 4(2), 76-82. PMCID: PMC3676970. https://doi.org/10.1002/dta.384
Marques, P., Hansson, T., Isaksson, A., Walther, L., Jones, J., Lewis, D., & Jones, M. (2011). Detection of phosphatidylethanol (PEth) in the blood of drivers in an alcohol ignition interlock program. Traffic Injury Prevention, 12(2), 136-141. PMCID: PMC3077108. https://doi.org/10.1080/15389588.2010.544048
Marques, P., Tippetts, S., Allen, J., Javors, M., Alling, C., Yegles, M., Pragst, F., & Wurst, F. (2010). Estimating driver risk using alcohol biomarkers, interlock blood alcohol concentration tests and psychometric assessments: initial descriptives. Addiction, 105(2), 226-239. PMCID: PMC2825139. https://doi.org/10.1111/j.1360-0443.2009.02738.x
Marques, P. R., & Voas, R. B. (2010). Key features for ignition interlock programs. (DOT HS 811 262). Washington, DC: National Highway Traffic Safety Administration. https://www.nhtsa.gov/sites/nhtsa.dot.gov/files/811262.pdf
Marques, P. R., Voas, R. B., Roth, R., & Tippetts, A. S. (2010). Evaluation of the New Mexico Ignition Interlock Program. (DOT HS 811 410). Washington, DC: National Highway Traffic Safety Administration. https://www.nhtsa.gov/sites/nhtsa.dot.gov/files/811410.pdf
Marques, P. R., & McKnight, A. S. (2009). Field and laboratory alcohol detection with 2 types of transdermal devices. Alcoholism: Clinical and Experimental Research, 33(4), 703-711. https://doi.org/10.1111/j.1530-0277.2008.00887.x
Marques, P. R., Pokorni, J. L., Long, T., & Teti, L. O. (2007). Maternal depression and cognitive features of 9-year-old children prenatally-exposed to cocaine. American Journal of Drug and Alcohol Abuse, 33(1), 45-61. https://doi.org/10.1080/00952990601082647
Marques, P. R., Tippetts, A. S., & Voas, R. B. (2003). Comparative and joint prediction of DUI recidivism from alcohol ignition interlock and driver records. Journal of Studies on Alcohol, 64(1), 83-92. https://doi.org/10.15288/jsa.2003.64.83
Marques, P. R., Tippetts, A. S., & Branch, D. G. (1993). Cocaine in the hair of mother–infant pairs: Quantitative analysis and correlations with urine measures and self-report. American Journal of Drug and Alcohol Abuse, 19(2), 159-175. https://doi.org/10.3109/00952999309002677